Anthropic Says Claude Designed 17 Scorpion Neurotoxin Binders in 64 Hours
Summary
Anthropic says its internal research model designed 17 protein binders that attach to scorpion neurotoxins, working mostly autonomously over 64 hours with four follow-up prompts. Of 211 designs tested by Adaptyv Bio and Twist Bioscience, 17 met the company's binding criteria. None has been tested in cells or animals, and Anthropic releases all 211 designs and their data.
Key Points
- Claude generated 318,484 designs and screened 553,052 design-toxin pairs using 12 design tools, Anthropic reports.
- None of the 91 multitoxin designs met Anthropic's binding criteria for more than one toxin, the company says.
- Cn2-B1 competes with antibody LR at the same epitope on the Cn2 toxin, which Anthropic says suggests it will likely neutralize the toxin.